Synthesis of some Cd(II) and Zn(II) complexes of a tetraazamacrocyclic ligand and their antimicrobial activities

Synthetic macrocycles specially the tetraazamacrocycles and their complexes have attracted considerable interests owing to their wide variety of applications. The ligand, 3, 10-C-meso- 3,5,7,7,10,12,14,14-octamethy1-1,4,8,11- tetraazacyclotetradeca-4,11-diene(L¹), upon reaction with CdI₂, Zn(ClO₄)₂, and Zn(CH₃COO)₂ produces corresponding square pyramidal cadmium (II) and zinc (II) complexes of formula [ML¹X]Y_n, (M = Cd or Zn; X = I, CH₃COO or H₂O; Y= I, ClO₄ or CH₃COO; n = 1 or 2). Among them, [CdL¹I]I and [ZnL¹(H₂O)](ClO₄)₂ undergo substitution reactions with KSCN and NaNO₂, respectively to produce octahedral trans- diisothiocyanatocadmium(II) complex, trans-[CdL¹(NCS)₂] and square pyramidal mononitratozinc(II) nitrate complex, [ZnL¹(NO₂)](NO₂). Antifimgal and antibacterial activities of these complexes against some of phytopathogenic fungi and bacteria have been investigated in this study.